Serena's best friend, Blair Waldorf (Leighton Meester), is the queen bee of Constance Billard, a prestigious private school. Blair's boyfriend, Nate Archibald (Chace Crawford), comes from a wealthy and influential family.
The series revolves around the lives of privileged upper-class teenagers on Manhattan's Upper East Side. The story begins with the introduction of Serena van der Woodsen (Blake Lively), a beautiful and popular teenager who returns to Manhattan after a mysterious absence.
The season premiered to 1.2 million viewers in the United States and spawned a successful series that ran for six seasons.